Lv1
20 积分 2024-03-26 加入
A Series of α-Amino Acid Ester Prodrugs of Camptothecin: In Vitro Hydrolysis and A549 Human Lung Carcinoma Cell Cytotoxicity
3个月前
已完结
Design, Synthesis, and Preliminary Evaluation of Doxazolidine Carbamates as Prodrugs Activated by Carboxylesterases
3个月前
已完结
Structural insights into CPT-11 activation by mammalian carboxylesterases
3个月前
已完结
Bioactivation of the anticancer agent CPT-11 to SN-38 by human hepatic microsomal carboxylesterases and the in vitro assessment of potential drug interactions
3个月前
已关闭
Hydrolysis of Capecitabine to 5′-Deoxy-5-fluorocytidine by Human Carboxylesterases and Inhibition by Loperamide
3个月前
已完结
Evaluating Prodrug Strategies for Esterase‐Triggered Release of Alcohols
3个月前
已完结
Water-Soluble Prodrugs of the Human Immunodeficiency Virus Protease Inhibitors Lopinavir and Ritonavir
3个月前
已完结
FimH Antagonists: Phosphate Prodrugs Improve Oral Bioavailability
3个月前
已完结
Enhancing the Oral Bioavailability of a Poorly Soluble Pan-CK2 Kinase Inhibitor: Leveraging a Phosphate Prodrug Strategy to Overcome Dissolution-Limited Absorption and Improve Systemic Exposure during Dose Escalation
3个月前
已完结
Prodrug Strategies to Improve the Solubility of the HCV NS5A Inhibitor Pibrentasvir (ABT-530)
3个月前
已完结
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