Lv2
106 积分 2025-05-08 加入
The elegant complexity of mammalian ecto-5'-nucleotidase (CD73)
1个月前
已完结
Pharmacological suppression of the OTUD4/CD73 proteolytic axis revives antitumor immunity against immune-suppressive breast cancers
1个月前
已完结
Hijacking ERAD for targeted degradation of transmembrane proteins
3个月前
已完结
An open-source drug discovery platform enables ultra-large virtual screens
5个月前
已完结
Combining IC50 or Ki Values From Different Sources is a Source of Significant Noise
6个月前
已完结
Deep contrastive learning enables genome-wide virtual screening
6个月前
已完结
Targeting the Spliceosomal Protein USP39 Through Allosteric Ligands and PROTAC‐Induced Degradation
8个月前
已完结
Development of selective FGFR1 degraders using a Rapid synthesis of proteolysis targeting Chimera (Rapid-TAC) platform
9个月前
已完结
Cancer Selective Target Degradation by Folate-Caged PROTACs
9个月前
已完结
Discovery of novel potent covalent inhibitor-based EGFR degrader with excellent in vivo efficacy
9个月前
已完结