Lv4
610 积分 2025-04-15 加入
PheSA: An Open-Source Tool for Pharmacophore-Enhanced Shape Alignment
10天前
已完结
Electron-density informed effective and reliable de novo molecular design and lead optimization with ED2Mol
10天前
已完结
Pharmacophore-oriented 3D molecular generation toward efficient feature-customized drug discovery
10天前
已完结
Generating 3D small binding molecules using shape-conditioned diffusion models with guidance
10天前
已完结
Direct Ser797 Interacted Pteridine-7(8H)-one Derivatives as Highly Selective and Orally Available EGFRL858R/T790M/C797S Inhibitors
14天前
已完结
Improved Pharmacokinetic Profiles of HDAC6 Inhibitors via Cap Group Modifications
14天前
已完结
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome
14天前
已完结
Efficacy and safety of ervogastat alone and in combination with clesacostat in patients with biopsy-confirmed metabolic dysfunction-associated steatohepatitis and F2–F3 fibrosis (MIRNA): results from a phase 2, randomised, double-blind, double-dummy study
15天前
已完结
Discovery of a tricyclic farnesoid X receptor agonist HEC96719, a clinical candidate for treatment of non-alcoholic steatohepatitis
19天前
已完结
Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors
21天前
已完结
皖公网安备34019202002308
