Lv4
512 积分 2025-04-15 加入
Discovery of CNS Penetrant SOS1 Inhibitors for the Treatment of KRAS-Dependent Cancers
1个月前
已完结
Utilizing Molecular Dynamics and Mechanistic Pharmacokinetic Studies in the Design of Selective CDK2 Inhibitors
1个月前
已完结
Discovery of Potent FGFR2/3 Inhibitors to Overcome Mutation Resistance and Treat Achondroplasia
2个月前
已完结
Discovery of Rogocekib (CTX-712): A Potent and Selective CLK Inhibitor for Cancer Treatment
2个月前
已完结
Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology
2个月前
已完结
Discovery of Potent and Selective Covalent Inhibitors of HER2WT and HER2YVMA
2个月前
已完结
Discovery of Novel 5,6-Dihydro-4H-pyrido[2,3,4-de]quinazoline Irreversible Inhibitors Targeting Both Wild-Type and A775_G776insYVMA Mutated HER2 Kinases
2个月前
已完结
Discovery and first-time disclosure of CVN766, an exquisitely selective orexin 1 receptor antagonist
2个月前
已完结
Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core
2个月前
已完结
Structure-Guided Discovery of Novel Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitors
2个月前
已完结
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