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102 积分 2025-04-15 加入
Brain Penetration Optimization and Anti-neuroinflammation Evaluation of Potent 6-Methyl-7-azaindol-3-yl-quinazoline DYRK1A Inhibitors for Alzheimer’s Disease
12小时前
已完结
Discovery of Novel Oral Covalent Inhibitors Targeting Active GTP-Bound KRASG12C with Potent Antitumor Activity
13小时前
已完结
Discovery of Novel 2-(2-Benzimidazole)-Substituted Tetrahydrofur-ans as Potent and Selective NaV1.8 Inhibitors for the Treatment of Pain
13小时前
已完结
Discovery of tetrasubstituted quinazolin-4(3H)-ones as wild-type-sparing, highly selective PI3K H1047R inhibitors
14小时前
已完结
Spirocyclic Scaffolds in Medicinal Chemistry
5天前
已完结
Successful and Unsuccessful Prediction of Human Hepatic Clearance for Lead Optimization
5天前
已完结
Recent Scaffold Hopping Applications in Central Nervous System Drug Discovery
5天前
已完结
Deuterated Drugs: Isotope Distribution and Impurity Profiles
5天前
已完结
Triazoles in Medicinal Chemistry: Physicochemical Properties, Bioisosterism, and Application
5天前
已完结
A Medicinal Chemistry Perspective on FDA-Approved Small Molecule Drugs with a Covalent Mechanism of Action
5天前
已完结
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