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54 积分 2022-02-17 加入
RMC-5127, a RAS(ON) G12V-selective inhibitor, drives durable tumor regressions and increases T cell infiltration in KRAS G12V-driven syngeneic models
22天前
已关闭
Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction
1个月前
已完结
Targeting the lipid metabolism proteins FASN and GPAM in alveolar type II cells decreases lung metastasis
1个月前
已完结
Cancer interception with KRAS inhibitors in preclinical models of pancreatic ductal adenocarcinoma
1个月前
已完结
A GPX1-OSBPL8 axis mediates noncanonical in vivo ferroptosis and cancer growth suppression
2个月前
已完结
Direct targeting of KRASG12X mutant cancers with RMC-6236, a first-in-class, RAS-selective, orally bioavailable, tri-complex RASMULTI(ON) inhibitor
2个月前
已完结
Direct targeting of KRASG12X mutant cancers with RMC-6236, a first-in-class, RAS-selective, orally bioavailable, tri-complex RASMULTI(ON) inhibitor
2个月前
已关闭
CB-6644 Is a Selective Inhibitor of the RUVBL1/2 Complex with Anticancer Activity
3个月前
已完结
Cancer cells co-opt an inter-organ neuroimmune circuit to escape immune surveillance
6个月前
已完结
Multimetric MRI Captures Early Response and Acquired Resistance of Pancreatic Cancer to KRAS Inhibitor Therapy
6个月前
已完结
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