Lv1
20 积分 2024-06-18 加入
Targeting cancer with small molecule pan-KRAS degraders
12小时前
已完结
B-cell lymphoma 6 in breast cancer: molecular mechanisms and clinical significance
9天前
已完结
Combination strategies with PARP inhibitors in BRCA-mutated triple-negative breast cancer: overcoming resistance mechanisms
10天前
已完结
Discovery of Reversible Covalent Bruton’s Tyrosine Kinase Inhibitors PRN473 and PRN1008 (Rilzabrutinib)
12天前
已完结
Application of Dually Activated Michael Acceptor to the Rational Design of Reversible Covalent Inhibitor for Enterovirus 71 3C Protease
12天前
已完结
Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma
18天前
已完结
Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update
20天前
已完结
Don’t Lose Your (War)head: Structure–Activity Relationships of Covalent Warheads as Substrates for GST-Catalyzed Glutathione Conjugation
20天前
已完结
Structural Modification of Tranilast against Poxvirus Based on α, β-Unsaturated Acrylamide Covalent Warhead and Confirmation of the Targets and Mode of Action
20天前
已完结
Discovery of New OTUB1 Covalent Ligands via Structure–Activity Relationship Studies for Targeted Protein Stabilization
21天前
已完结