Lv1
50 积分 2024-10-03 加入
Discovery of SY-589, a Highly Potent and Orally Bioavailable Polθ Helicase Inhibitor for the Treatment of HR-Deficient Tumors
5天前
已完结
Discovery of [1,2,4]Triazolo[4,3-a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction
22天前
已完结
Progress in PD-1/PD-L1 pathway inhibitors: From biomacromolecules to small molecules
22天前
已完结
Novel Small-Molecule PD-L1 Inhibitor Induces PD-L1 Internalization and Optimizes the Immune Microenvironment
26天前
已完结
Synthesis and preliminary evaluation of aminophenol derivatives as molecular glues blocking PD-1/PD-L1 interaction
27天前
已完结
Discovery of novel resorcinol biphenyl ether-based macrocyclic small molecules as PD-1/PD-L1 inhibitors with favorable pharmacokinetics for cancer immunotherapy
27天前
已完结
Discovery of BMS-986458, a Potent and Selective B-Cell Lymphoma 6 Protein Ligand-Directed Degrader, for the Treatment of B-Cell Non-Hodgkin Lymphoma
1个月前
已完结
Development of PD-L1 Targeting Small-Molecule Immunotheranostic Agents for Personalized Antitumor Immunotherapy
1个月前
已完结
Structural optimization of AR and AR-V7 degraders incorporating silicon-based hydrophobic tags for treatment of castration-resistant prostate cancer
1个月前
已关闭
Diversified Design Strategies for Small-molecule PROTACs: How Do We Select?
1个月前
已完结
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