Lv4
460 积分 2023-05-26 加入
Discovery of a VHL molecular glue degrader of GEMIN3 by Picowell RNA-seq
16天前
已完结
Inhibition of lysine acetyltransferase KAT6 in ER+HER2− metastatic breast cancer: a phase 1 trial
2个月前
已完结
Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein
2个月前
已完结
Discovery of SD-965 as a Potent, Selective, and Efficacious STAT3 PROTAC Degrader
2个月前
已完结
CC-92480, a Potent, Novel Cereblon E3 Ligase Modulator (CELMoD) Agent, in Combination with Dexamethasone (DEX) and Bortezomib (BORT) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Preliminary Results from the Phase 1/2 Study CC-92480-MM-002
2个月前
已关闭
Radioactive ADME Demonstrates ARV-110’s High Druggability Despite Low Oral Bioavailability
2个月前
已完结
SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate
2个月前
已完结
NDA Submission of Vepdegestrant (ARV-471) to U.S. FDA: The Beginning of a New Era of PROTAC Degraders
5个月前
已完结
Direct-to-Biology Enabled Molecular Glue Discovery
5个月前
已完结
A phase 1, first-in-human, open label, escalation and expansion study of ORM-5029, a highly potent GSPT1 degrader targeting HER2, in patients with HER2-expressing advanced solid tumors
5个月前
已完结
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