Lv4
470 积分 2023-05-26 加入
Direct-to-Biology Enabled Molecular Glue Discovery
3小时前
待确认
A phase 1, first-in-human, open label, escalation and expansion study of ORM-5029, a highly potent GSPT1 degrader targeting HER2, in patients with HER2-expressing advanced solid tumors
3天前
已完结
A novel ROR1-targeting antibody-PROTAC conjugate promotes BRD4 degradation for solid tumor treatment
13天前
已完结
In Silico-Driven THIOMAB Approach for Stable PROTAC Conjugates by Docking Payloads in Antibody Cavities
13天前
已完结
Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity
24天前
已完结
Degrader–Antibody Conjugates: Emerging New Modality
24天前
已完结
Degrader-antibody conjugates
24天前
已完结
Structure-Based Design of “Head-to-Tail” Macrocyclic PROTACs
1个月前
已完结
Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)
1个月前
已完结
Discovery of a Novel CRBN-Recruiting cGAS PROTAC Degrader for the Treatment of Ulcerative Colitis
1个月前
已完结
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