Lv4
602 积分 2025-03-11 加入
Comprehensive preclinical pharmacokinetic evaluations of trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, in cynomolgus monkeys
1个月前
已完结
Homogeneous antibody-drug conjugates with dual payloads: potential, methods and considerations
1个月前
已完结
Aqualigase: A Star Enzyme for One-Step Peptide Bond Dehydration Condensation in a Nature Aqueous Phase
3个月前
已完结
Discovery of RMC-6291, a potent, orally bioavailable, covalent RAS(ON) G12C selective inhibitor
5个月前
已完结
Indirect Effects Modulating the Interaction between DNA and a Cytotoxic Bisnaphthalimide Reveal a Two-Step Binding Process
5个月前
已完结
Hybrid Pharmacophore Design and Synthesis of Naphthalimide– Benzimidazole Conjugates as Potential Anticancer Agents
5个月前
已完结
DNA damage and intercalation by elinafide modified bis-naphthalimides for their anticancer activity
5个月前
已完结
An EORTC-ECSG phase I study of LU 79553 administered every 21 or 42 days in patients with solid tumours
5个月前
已关闭
Discovery of SY-589, a Highly Potent and Orally Bioavailable Polθ Helicase Inhibitor for the Treatment of HR-Deficient Tumors
5个月前
已完结
DB-1303, a HER2-targeting ADC with a novel DNA topoisomerase I inhibitor, demonstrates a promising safety profile and anti-tumor efficacy with differentiation from DS-8201a
5个月前
已完结
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