Lv51
1272 积分 2025-03-06 加入
Antitumor Efficacy of 1,2,4-Triazole-Based VCP/p97 Allosteric Inhibitors
1小时前
已完结
Small-Molecule Modulators of the ATPase VCP/p97 Affect Specific p97 Cellular Functions
1小时前
已完结
Sulfilimines from a Medicinal Chemist’s Perspective: Physicochemical and in Vitro Parameters Relevant for Drug Discovery
8天前
已完结
74636 Results from an Open-Label Phase 2 Trial of ATI-2138, an investigational oral covalent inhibitor of interleukin-2-inducible T cell kinase (ITK) and Janus kinase 3 (JAK3), in patients with moderate-to-severe atopic dermatitis
10天前
已关闭
Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors
19天前
已完结
Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition
26天前
已完结
Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans
26天前
已完结
PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor
26天前
已完结
Highly Effective Procedure for Introduction of Amino Group into the 2-Position of Imidazole Ring
1个月前
已完结