Lv31
346 积分 2024-09-20 加入
Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability
8小时前
已完结
Discovery of Highly Potent and Selective IKZF2 Degraders for Cancer Immunotherapy
2天前
已完结
Discovery of a Highly Potent and Selective mTOR Inhibitor that Strongly Suppresses Glioblastoma Multiforme Cell Growth
2天前
已完结
Optimization of Covalent 6-Cyanoquinazoline KRAS G12C Inhibitors for the Treatment of Solid Tumors
2天前
已完结
Design, Synthesis, and Biological Activity of Marinacarboline Analogues as STAT3 Pathway Inhibitors for Docetaxel-Resistant Triple-Negative Breast Cancer
14天前
已完结
Discovery of potent and selective STAT3 inhibitors against triple-negative breast cancer
14天前
已完结
Design and Synthesis of EZH2-Based PROTACs to Degrade the PRC2 Complex for Targeting the Noncatalytic Activity of EZH2
21天前
已完结
Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2
21天前
已完结
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
21天前
已完结
Discovery of a Novel Covalent EZH2 Inhibitor Based on Tazemetostat Scaffold for the Treatment of Ovarian Cancer
21天前
已完结
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