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488 积分 2026-02-23 加入
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
1个月前
已完结
Deubiquitinases in cancer
1个月前
已完结
Identification and Optimization of Pyridone Derivatives as Pan-MEK/RAF Nondegrading Molecular Glues for the Treatment of RAS-Driven Cancers
2个月前
已完结
The NanoBiT-Based Homogenous Ligand–Receptor Binding Assay
3个月前
已完结
Abstract CT268: Preliminary results from a first-in-human study of IK-595, an oral MEK/RAF molecular glue, in patients with RAS- or RAF-altered advanced solid tumors
3个月前
已完结
RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer
3个月前
已完结
A molecular glue halts RAS–MAPK signaling
4个月前
已完结
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
4个月前
已完结
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