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351 积分 2021-01-18 加入
Rapid Discovery of Celastrol Derivatives as Potent and Selective PRDX1 Inhibitors via Microplate-Based Parallel Compound Library and In Situ Screening
4小时前
已完结
Allosteric modulation and biased signalling at free fatty acid receptor 2
4小时前
已完结
Structures of butyrophilin multimers reveal a plier-like mechanism for Vγ9Vδ2 T cell receptor activation
7天前
已完结
Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen
15天前
已完结
Protein Crystallography and Drug Discovery
1个月前
已完结
PROTEIN CRYSTALLOGRAPHY AND DRUG DISCOVERY
1个月前
已完结
Discovery of Edecesertib (GS-5718): A Potent, Selective Inhibitor of IRAK4
1个月前
已完结
Rational Design of Dual Degraders by Incorporating Molecular Glue Structural Features into PROTAC Degraders
1个月前
已完结
Discovery of Novel Cyclic Peptides as SMAD2–SMAD4 Interaction Inhibitors for the Treatment of Hepatic Fibrosis
1个月前
已完结
Structural basis for nucleolin recognition of MYC promoter G-quadruplex
2个月前
已完结
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