Lv42
729 积分 2021-01-18 加入
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
8天前
已完结
PDE5a Inhibition Restricts Cancer Metastasis by Disrupting NPC1-Mediated Cholesterol Trafficking Through a Non-canonical cGMP-Dependent Pathway
8天前
已完结
Discovery of a Novel HSP90-Targeting Inhibitor for AML from the Marine Aaptamine Scaffold
21天前
已完结
Tumor-infiltrating plasma cell profiling after PD-1 blockade reveals tumor-specific antibodies
21天前
已完结
Structure-Based Design of Potent TLR7/8/9 Triple Antagonists: Overcoming High Tissue Distribution and Reactive Metabolite Liabilities
21天前
已完结
Relocalizing transcriptional kinases to activate apoptosis
27天前
已完结
Rewiring cancer drivers to activate apoptosis
27天前
已完结
A Bivalent Molecular Glue Linking Lysine Acetyltransferases to Oncogene-induced Cell Death
28天前
已完结
Exploring Privileged Structure Repurposing: Target Similarity as a Catalyst for Cross-Species Drug Discovery
28天前
已完结
Evaluating generalization in protein–ligand cofolding methods
1个月前
已完结
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