Lv11
30 积分 2025-02-27 加入
Characterization of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism
1小时前
待确认
Design, synthesis, structure-activity relationship (SAR) and analgesic effect studies of novel arylsulfonamides as selective Nav1.7 inhibitors
24天前
已完结
The synergistic anti-nociceptive effects of nefopam and gabapentinoids in inflammatory, osteoarthritis, and neuropathic pain mouse models
27天前
已完结
Microwave-assisted one-pot green synthesis, ADMET profiling, DFT, and molecular docking of novel 3-cyano-2-pyridone derivatives as dual EGFR and cytokine (TNF-α, IL-6) inhibitors
27天前
已完结
Dual-targeting Approach on Histamine H3 and Sigma-1 Receptor Ligands as Promising Pharmacological Tools in the Treatment of CNS-linked Disorders
29天前
已完结
Synthesis of thiazolidine-2,4-dione tethered 1,2,3-triazoles as α-amylase inhibitors: In vitro approach coupled with QSAR, molecular docking, molecular dynamics and ADMET studies
1个月前
已完结
Discovery and optimization of phenazopyridine hydrochloride as novel SARS-CoV-2 RdRp inhibitors
1个月前
已完结
Rational design and optimization of novel 4-methyl quinazoline derivatives as PI3K/HDAC dual inhibitors with benzamide as zinc binding moiety for the treatment of acute myeloid leukemia
1个月前
已完结
Structure-based screening, optimization and biological evaluation of novel chrysin-based derivatives as selective PPARγ modulators for the treatment of T2DM and hepatic steatosis
1个月前
已完结
Transition Metal‐Free, Visible Light‐Mediated Radical Cyclisation of Malonyl Radicals onto 5‐Ring Heteroaromatics
1个月前
已完结
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