Lv515
1348 积分 2025-07-10 加入
Discovery of 2-Chloro-pyrrolo[2,3-d]pyrimidin-4-one Derivatives as Protein Disulfide Isomerase Inhibitors with a Novel Allosteric-Covalent Binding Mode and Anti-Glioblastoma Activity
6天前
已完结
Discovery of a Novel Phenyl Thiophene-3-carboxamide Derivative DZX19 as an Orally TRK Inhibitor with Potent Antitumor Effects
23天前
已完结
Discovery of a Trifluoromethoxy Cyclopentanone Benzothiazole Receptor-Interacting Protein Kinase 1 Inhibitor as the Treatment for Alzheimer’s Disease
26天前
已完结
Dioxin receptor is a ligand-dependent E3 ubiquitin ligase
1个月前
已完结
Recent Updates on Indole Derivatives as Kinase Inhibitors in the Treatment of Cancer
1个月前
已完结
HtrA Protease Family as Therapeutic Targets
1个月前
已完结
A dual PROTAC nanocarrier amplifies DNA damage and STING activation for cancer immunotherapy
1个月前
已完结
Targeting HDAC and PARP Enhances STING‐Dependent Antitumor Immunity in STING‐Deficient Tumor
1个月前
已完结
DCAF11 Supports Targeted Protein Degradation by Electrophilic Proteolysis-Targeting Chimeras
1个月前
已完结
Arylidene-Thiazoldione Scaffold Acts as the E3 Ligand of DCAF11 for PROTAC Design
1个月前
已完结
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