医学
抗生素
植入
全髋关节置换术
变形杆菌
外科
感染率
全髋关节置换术
髋关节置换术
作者
Buchholz Hw,RA Elson,Engelbrecht E,H Lodenkamper,Röttger J,Siegel A
出处
期刊:Journal of Bone and Joint Surgery-british Volume
日期:1981-08-01
卷期号: (3): 342-353
被引量:609
标识
DOI:10.1302/0301-620x.63b3.7021561
摘要
Exchange operation is recommended as the treatment of choice for most deep infections involving a total hip replacement. This revision arthroplasty comprises, in one stage, excision of soft tissue, removal of implant and cement, replacement with an appropriate implant using Palacos R acrylic cement loaded with an appropriate antibiotic and, more recently, systemic antibiotics. During our first 10 years without systemic antibiotics we have achieved an overall 77 per cent success rate from a first attempt in 583 patients and a 90 per cent success rate after subsequent exchange procedures. Morbidity is significant but acceptable. Success is defined as control of infection, no loosening, and useful function. The factors associated with failures include, in particular, specific infections (Pseudomonas group, Streptococcus group D, Proteus group, and Escherichia coli), delay in operation and inadequate antibiotic dosage in the cement.
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