Fulminant Lymphocytic Myocarditis During Pregnancy Treated With Temporary Mechanical Circulatory Supports and Aggressive Immunosuppression

HomeCirculation: Heart FailureVol. 15, No. 12Fulminant Lymphocytic Myocarditis During Pregnancy Treated With Temporary Mechanical Circulatory Supports and Aggressive Immunosuppression No AccessCase ReportRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissionsDownload Articles + Supplements ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toSupplemental MaterialNo AccessCase ReportRequest AccessFull TextFulminant Lymphocytic Myocarditis During Pregnancy Treated With Temporary Mechanical Circulatory Supports and Aggressive Immunosuppression Giacomo Veronese, Sandra Nonini, Aldo Cannata, Francesca Aresta, Guido Olivieri, Elisa Montrasio, Daniele De Caria, Enrico Perna, Angelo Calini, Maurizio Bottiroli, Francesca Cislaghi, Giovanna Pedrazzini, Federica Baltaro, Giuseppina Quattrocchi, Patrizia Pedrotti, Claudio F. Russo, Andrea Garascia, Michele Mondino and Enrico Ammirati Giacomo VeroneseGiacomo Veronese Giacomo Veronese, MD, Department of Health Sciences, University of Milano-Bicocca, Piazza dell’Ateneo Nuovo, 1, 20126, Milan, Italy, Email E-mail Address: [email protected] https://orcid.org/0000-0002-6257-729X Department of Health Sciences, University of Milano-Bicocca, Milan, Italy (G.V.). *G. Veronese and S. Nonini contributed equally. Search for more papers by this author , Sandra NoniniSandra Nonini https://orcid.org/0000-0001-7335-7631 “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). *G. Veronese and S. Nonini contributed equally. Search for more papers by this author , Aldo CannataAldo Cannata https://orcid.org/0000-0002-8206-3536 “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Francesca ArestaFrancesca Aresta “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Guido OlivieriGuido Olivieri https://orcid.org/0000-0001-7597-5492 “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Elisa MontrasioElisa Montrasio “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Daniele De CariaDaniele De Caria “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Enrico PernaEnrico Perna “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Angelo CaliniAngelo Calini “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Maurizio BottiroliMaurizio Bottiroli “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Francesca CislaghiFrancesca Cislaghi “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Giovanna PedrazziniGiovanna Pedrazzini “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Federica BaltaroFederica Baltaro Department of Obstetrics and Gynecology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (F.B.). Search for more papers by this author , Giuseppina QuattrocchiGiuseppina Quattrocchi “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Patrizia PedrottiPatrizia Pedrotti https://orcid.org/0000-0001-8920-1156 “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Claudio F. RussoClaudio F. Russo “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Andrea GarasciaAndrea Garascia “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author , Michele MondinoMichele Mondino “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author and Enrico AmmiratiEnrico Ammirati Correspondence to: Enrico Ammirati, MD, PhD, “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore, 3, 20162, Milan, Italy, Email E-mail Address: [email protected] https://orcid.org/0000-0002-1676-5257 “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (S.N., A. Cannata, F.A., G.O., E.M., D.D.C., E.P., A. Calini, M.B., F.C., G.P., G.Q., P.P., C.F.R., A.G., M.M., E.A.). Search for more papers by this author Originally published28 Oct 2022https://doi.org/10.1161/CIRCHEARTFAILURE.122.009810Circulation: Heart Failure. 2022;15Footnotes*G. Veronese and S. Nonini contributed equally.Supplemental Material is available at https://www.ahajournals.org/doi/suppl/10.1161/CIRCHEARTFAILURE.122.009810.REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT05150704.For Sources of Funding and Disclosures, see page 1162.Correspondence to: Enrico Ammirati, MD, PhD, “De Gasperis” Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore, 3, 20162, Milan, Italy, Email enrico.[email protected]itGiacomo Veronese, MD, Department of Health Sciences, University of Milano-Bicocca, Piazza dell’Ateneo Nuovo, 1, 20126, Milan, Italy, Email veronese.[email protected]comReferences1. Ammirati E, Veronese G, Bottiroli M, Wang DW, Cipriani M, Garascia A, Pedrotti P, Adler ED, Frigerio M. Update on acute myocarditis. Trends Cardiovasc Med. 2021; 31:370–379. doi: 10.1016/j.tcm.2020.05.008CrossrefMedlineGoogle Scholar2. Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, et al. Management of acute myocarditis and chronic inflammatory cardiomyopathy: an expert consensus document. Circ Heart Fail. 2020; 13:e007405. doi: 10.1161/CIRCHEARTFAILURE.120.007405LinkGoogle Scholar3. Baritussio A, Schiavo A, Basso C, Giordani AS, Cheng CY, Pontara E, Cattini MG, Bison E, Gallo N, De Gaspari M, et al. Predictors of relapse, death or heart transplantation in myocarditis before the introduction of immunosuppression: negative prognostic impact of female gender, fulminant onset, lower ejection fraction and serum autoantibodies. Eur J Heart Fail. 2022; 24:1033–1044. doi: 10.1002/ejhf.2496CrossrefMedlineGoogle Scholar4. 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J Am Heart Assoc. 2020; 9:e016072. doi: 10.1161/JAHA.119.016072LinkGoogle Scholar10. Ammirati E, Bizzi E, Veronese G, Groh M, Van de Heyning CM, Lehtonen J, de Chambrun MP, Cereda A, Picchi C, Trotta L, et al. Immunomodulating Therapies in acute myocarditis and recurrent/acute pericarditis. Front Med (Lausanne). 2022; 9:838564. doi: 10.3389/fmed.2022.838564CrossrefMedlineGoogle Scholar Previous Back to top Next FiguresReferencesRelatedDetailsCited By Ammirati E and Moslehi J (2023) Diagnosis and Treatment of Acute Myocarditis, JAMA, 10.1001/jama.2023.3371, 329:13, (1098), Online publication date: 4-Apr-2023. December 2022Vol 15, Issue 12 Advertisement Article InformationMetrics © 2022 American Heart Association, Inc.https://doi.org/10.1161/CIRCHEARTFAILURE.122.009810PMID: 36305298 Originally publishedOctober 28, 2022 Keywordsendomyocardial biopsyshocktroponin Tfulminant myocarditisimmunosuppression therapyheart failuremechanical circulatory supportPDF download Advertisement SubjectsHeart FailureInflammatory Heart Disease