肠道菌群
普雷沃菌属
生物
食品科学
葡萄籽提取物
拟杆菌
生物化学
新陈代谢
双歧杆菌
失调
乳酸菌
细菌
医学
发酵
病理
替代医学
基因
遗传学
16S核糖体RNA
作者
Lanlan Du,Han Lv,Yan Chen,Xiaohua Yu,Tunyu Jian,Huifang Zhao,Wenlong Wu,Xiaoqin Ding,Jian Chen,Weilin Li
标识
DOI:10.1021/acs.jafc.3c04606
摘要
. Additionally, the supplementation with VA and RA reversed the elevated levels of valeric, caproic, and isovaleric acids observed in the high-fat diet (HFD) group, bringing them closer to the levels observed in the Chow group. This reversal indicated that alterations in the composition and abundance of gut microbiota may contribute to the restoration of short-chain fatty acids (SCFAs) levels. Additionally, PICRUSt2 exhibited that cyanamino acid metabolism and betalain biosynthesis might be the major metabolic pathways in the HVA group compared with the HFD group, while in the HRA group, it was the phosphotransferase system. These findings suggest that VA and RA can ameliorate MetS by modulating the gut microbiota and production of SCFAs.
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