生物
机制(生物学)
免疫系统
肠道菌群
动物
工蜂
养蜂女孩
生态学
微生物学
免疫学
认识论
哲学
作者
Hongfang Wang,Li Lei,Wenfeng Chen,Xuepeng Chi,Kai Han,Zhenguo Liu,Liming Ma,Zhenguo Liu,Baohua Xu
出处
期刊:Insects
[MDPI AG]
日期:2022-08-26
卷期号:13 (9): 772-772
被引量:2
标识
DOI:10.3390/insects13090772
摘要
Queen bees and worker bees both develop from fertilized eggs, whereas queens live longer than workers. The mechanism of this phenomenon is worth exploring. Antioxidant capacity, immune and IIS are the conserved mechanisms of aging. The importance of gut bacteria for health prompted us to connect with bee aging. Therefore, the differences of antioxidant, immune, IIS and gut microflora between queen and worker bees were compared to find potential mechanisms of queens' longevity. The results showed queens had stronger antioxidant capacity and lower immune pathway and IIS activity than workers. The higher expression level of catalase and SOD1/2 in queens resulted in the stronger ROS scavenging ability, which leads to the lower ROS level and the reduced accumulation of oxidative damage products in queens. The lower IMD expression and higher antimicrobial peptides (AMPs) expressions in queens suggested that queens maintain lower immune pathway activity and stronger immune capacity than workers. Gut bacteria composition analysis indicated that queens had supernal Acetobacteraceae (notably Commensalibacter and Bombella), Lactobacillus and Bifidobacterium over workers. In conclusion, antioxidant, immune, IIS, and gut symbiotic bacteria all contribute to the longevity of queens. This study provides more insights into revealing the mechanisms of queens' longevity.
科研通智能强力驱动
Strongly Powered by AbleSci AI