Endoscopic diagnosis and treatment of 403 cases of laterally spreading tumor in colon

Objective To explore the clinical and pathological features of laterally spreading tumor (LST) in colon, and the efficacy and safety of endoscopic submucosal dissection (ESD). Methods A total of 376 cases with 403 lesions of LST were detected by colonoscopy in the First Hospital of China Medical University from April 2014 to December 2016. The site, size and classification of all lesions were recorded. One hundred and sixty lesions in 143 patients underwent endoscopic treatment, and Their pit pattern were observed. The resected lesions were sent for pathological examination. The patients were followed up regularly after treatment. Results Among 403 cases of LST, 168 lesions (41.69%) were located at rectum, which was the main site. Lesions with diameter of 10- 0.05) showed an increasing trend with the upgrade of pit pattern of LST cases. Among the 128 patients who were treated by ESD, 113 cases were regularly reexamined, and 2 cases relapsed. Others whose wounds didn′t relapse healed well. Conclusion The clinical and pathological features of colorectal LST are unique. ESD is an effective and safe treatment for LST, which can achieve radical results. Key words: Colorectal neoplasms; Endoscopy; Pit pattern; Colorectal laterally spreading tumor