操纵子
生物
基因
遗传学
大肠杆菌
基因簇
原噬菌体
基因组
质粒
打开阅读框
噬菌体
肽序列
出处
期刊:DNA Research
[Oxford University Press]
日期:1996-01-01
卷期号:3 (6): 363-377
被引量:33
标识
DOI:10.1093/dnares/3.6.363
摘要
The 569,750 base pair sequence corresponding to the 28.0–40.1 min region on the genetic map of Escherichia coli K-12 (W3110) was determined. This region includes the replication terminus region and contained at least 549 potential open reading frames. Among them, 160 (29%) were previously reported, 174 (32%) were homologous to other known genes, 102 (18%) were identical or similar to hypothetical genes registered in databases, and the remaining 113 (21%) did not show a significant similarity to any other gene. Of interest was the finding of a large number of genes and gene clusters in andnear the replication termination region which had been thought to be genetically silent. Those includeda cluster of genes for fatty acid β-oxidation, the third copy of the pot (spermidine/putrescine transport system) gene cluster, the second dpp (dipeptide transport system) operon, the second dsm (anaerobic dimethyl sulfoxide reductase) operon, a cluster of fim (fimbrial) genes anda DNA helicase-like gene with a high molecular weight. In addition, we found the dnaC - and dnaT -like genes in the cryptic prophage, Rac, anda number of genes originated probably from plasmids.
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