Co3O4-chitosan/biomass-derived porous carbon molecularly imprinted polymer integrated electrode for selective detection of glucose

The detection of glucose (Glu) is of great significance in medical diagnosis, food processing and biotechnology. Rapid, accurate and convenient detection technology is particularly important. Herein, the Co 3 O 4 -PC nanocomposite grown on biomass-derived porous carbon (PC) was prepared by hydrothermal method and subsequent air calcination. Chitosan (CS) was electrodeposited on the surface of Co 3 O 4 -PC by potentiostatic deposition with Glu as the template molecule. Finally, the template molecule was eluted by cyclic voltammetry to create specific recognition sites for Glu, and a highly selective and stable Glu sensor was constructed. The obtained MIP (molecularly imprinted polymer)-Glu-CS/Co 3 O 4 /PC nanocomposites were characterized by scanning electron microscopy, Raman spectroscopy, cyclic voltammetry, chronoamperometry and so on. The results showed that the MIP-Glu-CS/Co 3 O 4 -PC had great catalytic performance for Glu detection with a linear range of 12.17 μM-2.3 mM, a detection limit of 4.01 μM, and a sensitivity of 407.5 μA cm −2 mM −1 . The sensor has excellent selectivity and stability. This work provides a guide for improving the selectivity of nanozymes.