Fetal edema, not overgrowth, is associated with neonatal lethal Costello syndrome due to the HRAS p.Gly12Val mutation

Greenwood Genetic Center, Greenwood, South Carolina, USA Correspondence to Roger E. Stevenson, MD, J.C. Self Research Institute of Human Genetics, Greenwood Genetic Center, 113 Gregor Mendel Circle, Greenwood, SC 29646, USA Tel: +1 864 941 8146; fax: +1 864 388 1707; e-mail: [email protected]