子痫前期
胎盘
怀孕
胎儿
产妇发病率
免疫系统
封面(代数)
医学
产科
生物信息学
免疫学
生物
遗传学
机械工程
工程类
作者
Christopher W.G. Redman,Ian L. Sargent
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2005-06-09
卷期号:308 (5728): 1592-1594
被引量:2541
标识
DOI:10.1126/science.1111726
摘要
Preeclampsia is a relatively common pregnancy disorder that originates in the placenta and causes variable maternal and fetal problems. In the worst cases, it may threaten the survival of both mother and baby. We summarize recent work on the causes of preeclampsia, which reveals a new mode of maternal immune recognition of the fetus, relevant to the condition. The circulating factors derived from the placenta, which contributes to the clinical syndrome, are now better understood. This brief review on preeclampsia does not cover all aspects of this intriguing condition but focuses on some new and interesting findings.
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