Vitamin B12 Controlled Release with Crosslinked Poly (Acrylic Acid) and Poly (Methacrylic Acid) Based on Chitosan and Starch as pH Sensitive Hydrogels

Background: Hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. But most of hydrogels are not biodegradable. Keywords: Acrylic acid, chitosan, hydrogel, methacrylic acid, pH sensitive, starch.