姜黄素
炎症
活性氧
药理学
化学
清除
肺
医学
免疫学
生物化学
抗氧化剂
内科学
作者
Renyikun Yuan,Yuqing Li,Shan Han,Xinxin Chen,Jingqi Chen,Jia He,Hongwei Gao,Yang Yang,Shilin Yang,Yu Yang
标识
DOI:10.1021/acscentsci.1c00866
摘要
T cells in mice, which could help suppress the inflammation cytokine storm caused by ALI. Overall, this work has developed the strategy of using Fe-Cur NPs as nanozymes to scavenge intracellular ROS and as an anti-inflammation nanodrugs to synergistically cure ALI, which may serve as a promising therapeutic agent in the clinical treatment of this deadly disease. Fe-Cur NP nanozymes were designed to attenuate ALI by clearing intracellular ROS and alleviating inflammation synergistically. Relevant cytokines, inflammasomes, and signaling pathways were studied.
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