止血
医学
血栓形成
组织因子
免疫学
内科学
凝结
作者
Tovo David,Yun Cheol Kim,Lauren K. Ely,Isaac J. Rondon,Huilan Gao,Peter J. O’Brien,Michael W. Bolt,Anthony J. Coyle,J. Luz Tovar García,Eric A. Flounders,Thomas Mikita,Shaun R. Coughlin
标识
DOI:10.1126/scitranslmed.aaf4331
摘要
A noneffector, active site–dependent human IgG1 specific to factor XIa inhibits thrombus formation in two animal models at clinically relevant doses without a detectable effect on hemostasis.
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