Effect of intermittent hemodialysis filtration mode on intradialytic hypotension and nutritional status in patients with end‐stage renal disease

Abstract Introduction This study aimed to investigate the effect of intermittent hemodialysis filtration mode ( IHDF ) on intradialytic hypotension and nutritional status in patients with end‐stage renal disease ( ESRD ). Methods Patients with ESRD who underwent hemodialysis and were treated at our hospital from December 2021 to December 2023 according to the inclusion and exclusion criteria were selected and randomly assigned into two groups: the experimental group (patients received intermittent hemodialysis filtration mode treatment, n = 50) and the control group (patients received conventional maintenance hemodialysis treatment, n = 49). Subsequently, the participant characteristics, the treatment effect, the occurrence of intradialytic hypotension, the safety assessment, blood pressure indicators, and the nutritional status were compared between the two groups. Results Compared to the control group, the experimental group had a better treatment effect, a lower incidence of hypotension, a lower rate of complications, and higher levels of albumin ( ALB ), hemoglobin (Hb), prealbumin ( PA ), transferrin ( SF ), diastolic blood pressure ( DBP ), systolic blood pressure ( SBP ), and mean arterial pressure ( MAP ). Conclusions IHDF could effectively improve the therapeutic effect of patients with ESRD , reduce the incidence of hypotension during dialysis, regulate blood pressure balance, maintain the nutritional level of patients, decrease the occurrence of complications, and have higher safety.