化学
纳米复合材料
Zeta电位
检出限
色氨酸
分析物
傅里叶变换红外光谱
阳离子聚合
比色法
偏最小二乘回归
色谱法
核化学
氨基酸
化学工程
纳米技术
有机化学
纳米颗粒
生物化学
材料科学
工程类
统计
数学
作者
Maryam Abbasi Tarighat,Fatemeh Naamdar
标识
DOI:10.1016/j.jpba.2023.115942
摘要
In the present study, a simple, innovative, and economically beneficial method has been proposed for the synthesis of Ag@Ag2O core-shell nanocomposites using Acanthophora muscoides algae extract. The host-guest recognition of targets was performed by modification of the Ag@Ag2O surface using β-CD. The Ag@Ag2O- β-CD NCs were used as a colorimetric sensor to determine L-Tryptophan and L-Tyrosine using a partial least square (PLS) approach. A crystalline hybrid structure of Ag core and an Ag2O shell was confirmed by XRD, FTIR, TEM and AFM research. Also, DLS analysis and surface zeta potential spectra illustrated the aggregated nature of nanocomposites in the presence of analytes. The literature review shows that the colorimetric simultaneous determination of L-Tryptophan (L-Try) and L-Tyrosine (L-Tyr) has not been reported. The Ag@Ag2O- β-CD sensor exhibited outstanding sensing capability in a broad linear range of 2.0 –200 μM for both amino acids and low detection limit of 0.32 and 0.51 μM, for L-Try and L-Tyr, respectively. The good sensitivity and excellent selectivity regarding possible interfering species, originated from the synergistic effect of host-guest recognition in combination with colorimetric sensing. Additionally, determination of analytes in various pharmaceutical, supplement and urine samples, approved the practical applicability of the constructed sensor. The computed results confirmed that colorimetric sensing in conjunction with a PLS technique was appropriate for the precise and accurate simultaneous determination of target amino acids in complex mixtures with RMSEP less than 2.5% and recovery in the range of 103–108% with R.S.D. values less than 3%.
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