化学
生物分析
位阻效应
组合化学
纳米技术
超分子化学
光化学
有机化学
分子
色谱法
材料科学
作者
Ping Yin,Zheng Li,Qiuhua Wu,Jin Hu,Feng‐Zao Chen,Guangxu Chen,Peng Lin,Deman Han,Weiwei Zhao
标识
DOI:10.1021/acs.analchem.3c04875
摘要
A facile route for exponential magnification of transconductance (gm) in an organic photoelectrochemical transistor (OPECT) is still lacking. Herein, photoresponsive hydrogen-bonded organic frameworks (PR-HOFs) have been shown to be efficient for gm magnification in a typical poly(ethylene dioxythiophene):poly(styrenesulfonate) OPECT. Specifically, 450 nm light stimulation of 1,3,6,8-tetrakis (p-benzoic acid) pyrene (H4TBAPy)-based HOF could efficiently modulate the device characteristics, leading to the considerable gm magnification over 78 times from 0.114 to 8.96 mS at zero Vg. In linkage with a DNA nanomachine-assisted steric hindrance amplification strategy, the system was then interfaced with the microRNA-triggered structural DNA evolution toward the sensitive detection of a model target microRNA down to 0.1 fM. This study first reveals HOFs-enabled efficient gm magnification in organic electronics and its application for sensitive biomolecular detection.
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