抗菌活性
粒径
化学
核化学
壳聚糖
分散性
纳米颗粒
最低杀菌浓度
离子强度
最小抑制浓度
傅里叶变换红外光谱
化学工程
抗菌剂
色谱法
Zeta电位
纳米技术
材料科学
水溶液
有机化学
细菌
物理化学
工程类
生物
遗传学
作者
Hongcai Zhang,Jooyeoun Jung,Yanyun Zhao
标识
DOI:10.1016/j.carbpol.2015.10.036
摘要
This study used β-chitosan nanoparticles (β-CS NPs) of different particle sizes to encapsulate catechins (CAT) or CAT-Zn complex by ionic gelation technology. The antibacterial activity of CAT or CAT-Zn complex loaded β-CS NPs against Escherichia coli and Listeria innocua were investigated based on bacterial growth curve, minimum inhibitory concentration (MIC), and minimum bacterial concentration (MBC). Fourier transform infrared spectrometer (FT-IR) was employed to study the incorporation of CAT or CAT-Zn complex into β-CS NPs. The CAT-Zn complex loaded β-CS NPs had particle size of 208-591 nm, polydispersity index (PDI) of 0.377-0.395, and positive Zeta-potential of 39.17-45.62 mV. The CAT-Zn complex loaded β-CS NPs of smaller particle sizes showed higher antibacterial activity than that of larger particle size ones. The MIC and MBC of CAT-Zn complex loaded β-CS NPs of the smallest particle size against L. innocua and E. coli were 0.031 and 0.063 mg/mL, and 0.063 and 0.125 mg/mL, respectively. This study suggested that encapsulation of CAT-Zn complex in β-CS NPs improved the antibacterial activity of CAT and CAT-Zn complex, and the encapsulators have great potential to be used as antibacterial substances for food and other applications through either direct addition or incorporation into packaging materials.
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