化学
异苯并呋喃
酰胺
苯甲酸
分子内力
蒂奥-
苯乙烯
有机化学
立体化学
药物化学
共聚物
聚合物
作者
Yunfei Du,Goutham Kommuru,Jingran Zhang,Yaxin Ouyang,Kang Zhao
出处
期刊:Synlett
[Georg Thieme Verlag KG]
日期:2022-04-18
卷期号:33 (13): 1266-1272
被引量:2
摘要
Abstract A divergent synthesis of isobenzofuran-1(3H)-one and 3,4-dihydroisochroman-1-one derivatives has been realized through the reaction of o-alkenyl benzoic acids/amides with PhICl2 and diphenyl disulfides/diselenides. Depending on the substitution type of the o-alkenyl benzoic acid or amide, this metal-free intramolecular oxychalcogenation approach regioselectively affords isobenzofuran-1(3H)-ones or 3,4-dihydroisochroman-1-ones through 5-exo-trig or 6-endo-trig cyclization processes, respectively.
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