[Expert consensus on immunoprophylaxis of childhood rotavirus gastroenteritis (2024 version)].

Rotavirus gastroenteritis (RVGE) is a global public health challenge that seriously threatens the health of children under 5 years of age. In China, the burden associated with RVGE is substantial and its prevention and control are difficult. On the basis of Expert Consensus on Immunoprophylaxis of Childhood Rotavirus Gastroenteritis (2020 Version) and Rotavirus Vaccines: WHO Position Paper-July 2021, in this updated consensus we systematically review advances in RVGE epidemiological research; safety, effectiveness/efficacy, and immune persistence of post-marketing rotavirus (RV) vaccines; and RV immunization strategies. We also provide guidance for RVGE diagnosis and treatment. Following the principles of prioritizing prevention and integrating medical and preventive approaches, we aim to facilitate the implementation of comprehensive prevention and control measures focusing on RV vaccination to reduce the childhood RVGE disease burden and provide reference for professionals working for disease control and prevention, vaccination, clinical diagnosis and treatment, and related fields.轮状病毒胃肠炎（RVGE）是严重威胁5岁以下儿童健康的全球性公共卫生问题。中国RVGE相关疾病负担重，防控难度大。本共识在《儿童轮状病毒胃肠炎免疫预防专家共识（2020版）》和《世界卫生组织轮状病毒疫苗立场文件—2021年7月》的基础上，系统综述了RVGE流行病学、已上市轮状病毒（RV）疫苗的安全性、有效性和免疫保护持久性、RV疫苗免疫策略等国内外研究进展，增补了常见的RVGE诊疗方案。本共识旨在从预防为主和医防融合的角度出发，推动落实以疫苗接种为重点的RVGE综合性防控措施，降低儿童RVGE疾病负担，为从事疾病预防控制、疫苗接种、临床诊疗等多领域的工作人员提供参考。.