新生儿重症监护室
多巴胺
医学
重症监护室
重症监护医学
儿科
内科学
作者
Mallory A. Prideaux,Ronnie Guillet
出处
期刊:Neoreviews
[American Academy of Pediatrics]
日期:2024-04-01
卷期号:25 (4): e207-e215
标识
DOI:10.1542/neo.25-4-e207
摘要
Abstract Dopamine has been used for half a century in adult and pediatric patients for the treatment of hypotension, as well as for the theoretical prevention of acute kidney injury (AKI). Although activation of renal dopamine receptors leads to increased urine output, there is no evidence that low-dose dopamine reduces the incidence of AKI, need for dialysis, or death. Dopamine administration is also associated with multiple adverse effects, particularly in preterm infants. Despite the lack of evidence for its use, as well as the known adverse effects of dopamine, many neonatologists still use low-dose dopamine to prevent or treat AKI in neonates. In this review, we provide a summary of our current medical knowledge about the use of low-dose dopamine in the neonatal population.
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