摘要
Journal of the European Academy of Dermatology and VenereologyEarly View LETTER TO THE EDITOR Long-term effectiveness and tolerability of apremilast in patients with moderate-to-severe plaque psoriasis: A 5-year multicentre retrospective study—IL PSO (Italian landscape psoriasis) L. Gargiulo, Corresponding Author L. Gargiulo [email protected] orcid.org/0000-0002-6051-1676 Dermatology Unit, IRCCS Humanitas Research Hospital, Milan, Italy Department of Biomedical Sciences, Humanitas University, Milan, Italy Correspondence Luigi Gargiulo, Department of Biomedical Sciences, Humanitas University, 20089, Rozzano (Milan), Italy. Email: [email protected]Search for more papers by this authorL. Ibba, L. Ibba orcid.org/0000-0002-7876-4866 Dermatology Unit, IRCCS Humanitas Research Hospital, Milan, Italy Department of Biomedical Sciences, Humanitas University, Milan, ItalySearch for more papers by this authorP. Malagoli, P. Malagoli Department of Dermatology, Dermatology Unit Azienda Ospedaliera San Donato Milanese, Milan, ItalySearch for more papers by this authorF. Amoruso, F. Amoruso Dermatology Unit, Azienda Ospedaliera di Cosenza, Cosenza, ItalySearch for more papers by this authorA. Balato, A. Balato orcid.org/0000-0001-5485-0172 Dermatology Unit, University of Campania L. Vanvitelli, Naples, ItalySearch for more papers by this authorF. Bardazzi, F. Bardazzi Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola Malpighi, Bologna, ItalySearch for more papers by this authorM. Burlando, M. Burlando Department of Dermatology, Dipartimento di Scienze Della Salute (DISSAL), University of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, ItalySearch for more papers by this authorC. G. Carrera, C. G. Carrera Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, ItalySearch for more papers by this authorP. Dapavo, P. Dapavo Department of Biomedical Science and Human Oncology, Second Dermatologic Clinic, University of Turin, Turin, ItalySearch for more papers by this authorV. Dini, V. Dini orcid.org/0000-0002-8537-1999 Dermatology Unit, Department of Clinical and Experimental Medicine Ospedale Santa Chiara, Pisa, ItalySearch for more papers by this authorF. M. Gaiani, F. M. Gaiani orcid.org/0009-0003-7613-4451 Department of Dermatology, Dermatology Unit Azienda Ospedaliera San Donato Milanese, Milan, ItalySearch for more papers by this authorG. Girolomoni, G. Girolomoni orcid.org/0000-0001-8548-0493 Department of Medicine, Section of Dermatology and Venereology, University of Verona, Verona, ItalySearch for more papers by this authorC. Guarneri, C. Guarneri Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Unit of Dermatology, University of Messina, AOU Policlinico G. Martino, Messina, ItalySearch for more papers by this authorC. Lasagni, C. Lasagni Dermatological Clinic, Department of Specialized Medicine, University of Modena, Modena, ItalySearch for more papers by this authorF. Loconsole, F. Loconsole Department of Dermatology, University of Bari, Bari, ItalySearch for more papers by this authorA. V. Marzano, A. V. Marzano orcid.org/0000-0002-8160-4169 Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy Department of Pathophysiology and Transplantation, Università Degli Studi di Milano, Milan, ItalySearch for more papers by this authorM. Maurelli, M. Maurelli orcid.org/0000-0001-7492-8010 Department of Medicine, Section of Dermatology and Venereology, University of Verona, Verona, ItalySearch for more papers by this authorM. Megna, M. Megna orcid.org/0000-0003-1803-2046 Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, ItalySearch for more papers by this authorM. Travaglini, M. Travaglini U.O.S.D. Dermatologica – Centro per la Cura Della Psoriasi, Brindisi, ItalySearch for more papers by this authorA. Costanzo, A. Costanzo orcid.org/0000-0001-9697-2557 Dermatology Unit, IRCCS Humanitas Research Hospital, Milan, Italy Department of Biomedical Sciences, Humanitas University, Milan, ItalySearch for more papers by this authorA. Narcisi, A. Narcisi Dermatology Unit, IRCCS Humanitas Research Hospital, Milan, ItalySearch for more papers by this author L. Gargiulo, Corresponding Author L. Gargiulo [email protected] orcid.org/0000-0002-6051-1676 Dermatology Unit, IRCCS Humanitas Research Hospital, Milan, Italy Department of Biomedical Sciences, Humanitas University, Milan, Italy Correspondence Luigi Gargiulo, Department of Biomedical Sciences, Humanitas University, 20089, Rozzano (Milan), Italy. Email: [email protected]Search for more papers by this authorL. Ibba, L. Ibba orcid.org/0000-0002-7876-4866 Dermatology Unit, IRCCS Humanitas Research Hospital, Milan, Italy Department of Biomedical Sciences, Humanitas University, Milan, ItalySearch for more papers by this authorP. Malagoli, P. Malagoli Department of Dermatology, Dermatology Unit Azienda Ospedaliera San Donato Milanese, Milan, ItalySearch for more papers by this authorF. Amoruso, F. Amoruso Dermatology Unit, Azienda Ospedaliera di Cosenza, Cosenza, ItalySearch for more papers by this authorA. Balato, A. Balato orcid.org/0000-0001-5485-0172 Dermatology Unit, University of Campania L. Vanvitelli, Naples, ItalySearch for more papers by this authorF. Bardazzi, F. Bardazzi Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola Malpighi, Bologna, ItalySearch for more papers by this authorM. Burlando, M. Burlando Department of Dermatology, Dipartimento di Scienze Della Salute (DISSAL), University of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, ItalySearch for more papers by this authorC. G. Carrera, C. G. Carrera Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, ItalySearch for more papers by this authorP. Dapavo, P. Dapavo Department of Biomedical Science and Human Oncology, Second Dermatologic Clinic, University of Turin, Turin, ItalySearch for more papers by this authorV. Dini, V. Dini orcid.org/0000-0002-8537-1999 Dermatology Unit, Department of Clinical and Experimental Medicine Ospedale Santa Chiara, Pisa, ItalySearch for more papers by this authorF. M. Gaiani, F. M. Gaiani orcid.org/0009-0003-7613-4451 Department of Dermatology, Dermatology Unit Azienda Ospedaliera San Donato Milanese, Milan, ItalySearch for more papers by this authorG. Girolomoni, G. Girolomoni orcid.org/0000-0001-8548-0493 Department of Medicine, Section of Dermatology and Venereology, University of Verona, Verona, ItalySearch for more papers by this authorC. Guarneri, C. Guarneri Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Unit of Dermatology, University of Messina, AOU Policlinico G. Martino, Messina, ItalySearch for more papers by this authorC. Lasagni, C. Lasagni Dermatological Clinic, Department of Specialized Medicine, University of Modena, Modena, ItalySearch for more papers by this authorF. Loconsole, F. Loconsole Department of Dermatology, University of Bari, Bari, ItalySearch for more papers by this authorA. V. Marzano, A. V. Marzano orcid.org/0000-0002-8160-4169 Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy Department of Pathophysiology and Transplantation, Università Degli Studi di Milano, Milan, ItalySearch for more papers by this authorM. Maurelli, M. Maurelli orcid.org/0000-0001-7492-8010 Department of Medicine, Section of Dermatology and Venereology, University of Verona, Verona, ItalySearch for more papers by this authorM. Megna, M. Megna orcid.org/0000-0003-1803-2046 Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, ItalySearch for more papers by this authorM. Travaglini, M. Travaglini U.O.S.D. Dermatologica – Centro per la Cura Della Psoriasi, Brindisi, ItalySearch for more papers by this authorA. Costanzo, A. Costanzo orcid.org/0000-0001-9697-2557 Dermatology Unit, IRCCS Humanitas Research Hospital, Milan, Italy Department of Biomedical Sciences, Humanitas University, Milan, ItalySearch for more papers by this authorA. Narcisi, A. Narcisi Dermatology Unit, IRCCS Humanitas Research Hospital, Milan, ItalySearch for more papers by this author First published: 29 March 2024 https://doi.org/10.1111/jdv.20003Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 European Medicines Agency. Otezla (apremilast): summary of product characteristics. 2015 [cited 2023 December 6]. Available from: https://www.ema.europa.eu/en/medicines/human/EPAR/otezla Google Scholar 2Nast A, Smith C, Spuls PI, Avila Valle G, Bata-Csörgö Z, Boonen H, et al. 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