化学
区域选择性
色氨酸
表面改性
催化作用
铑
醌
氨基酸
组合化学
立体化学
有机化学
生物化学
物理化学
作者
Disha Tank,Narendra Dinkar Kharat,Kiran Bajaj,Siva S. Panda,Rajeev Sakhuja
标识
DOI:10.1002/ajoc.202300503
摘要
Abstract Pivaloyl‐directed Rh(III)‐catalyzed regioselective C7 Ar ‐H functionalization of protected tryptophans were accomplished with 1,4‐benzoquinones, furnishing a series of quinone‐appended tryptophan‐based unnatural amino acids in high yields. Further, the late stage functionalization on tryptophan‐containing dipeptides was achieved with 1,4‐benzoquinones in moderate reactivity.
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