肺结核
抗细菌
蛋白酶体抑制剂
立体化学
生物化学
体外
细胞凋亡
作者
Wenhu Zhan,Hao-Chi Hsu,Trevor Morgan,Tierra Ouellette,Kristin Burns-Huang,Ryoma Hara,Adrian G. Wright,Toshihiro Imaeda,Rei Okamoto,Kenjiro Sato,Mayako Michino,Manoj K. Ramjee,Kazuyoshi Aso,Peter T. Meinke,Michael Foley,Carl Nathan,Huilin Li,Gang Lin
标识
DOI：10.1021/acs.jmedchem.9b01187
摘要
Proteasomes of pathogenic microbes have become attractive targets for anti-infectives. Coevolving with its human host, Mycobacterium tuberculosis (Mtb) has developed mechanisms to resist host-impos...
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