We hope to answer the following questions with this study: What are the most characteristic personality traits of students with creative talent? Are there personality traits that allow a subject to promote his or her creativity? Lastly, is there a relationship between these personality traits and a neurobiological basis for creativity? The results of this study should serve to identify and develop creative talents and to continue stimulating their divergent thinking. The BFQ-NA questionnaire, which evaluates five personality traits, and the CREA and PIC-N creativity tests, which measure creative intelligence and imagination, respectively, were administered to a sample of 244 students aged ten to twelve years old. The data from the statistical analysis indicate that Conscientiousness is the most predictive trait for creativity for CREA (B = 0.18, p < 0.001), as well as for PIC in terms of narrative creativity (B = 1.044, p < 0.001) and graphic creativity (B = 0.213, p = 0.003 and total B = 1.259, p < 0.001). Other statistically significant traits, albeit to a lesser degree than Conscientiousness, were Openness and Emotional Instability.