Targeted, triggered drug delivery to tumor and biofilm microenvironments

NanomedicineVol. 11, No. 8 CommentaryTargeted, triggered drug delivery to tumor and biofilm microenvironmentsDanielle SW Benoit & Hyun KooDanielle SW Benoit*Author for correspondence: E-mail Address: benoit@bme.rochester.edu Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA Department of Chemical Engineering, University of Rochester, Rochester, NY, USA Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USASearch for more papers by this author & Hyun Koo Biofilm Research Lab, Levy Center for Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA Department of Orthodontics & Divisions of Pediatric Dentistry & Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USASearch for more papers by this authorPublished Online:18 Mar 2016https://doi.org/10.2217/nnm-2016-0014AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail View articleKeywords: biofilmextracellular matrixmicroenvironmentnanomedicinenanoparticlestumorReferences1 Mura S, Nicolas J, Couvreur P. 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surface passivation, drug delivery and biofilm preventionAIMS Microbiology, Vol. 2, No. 4 Vol. 11, No. 8 STAY CONNECTED Metrics Downloaded 557 times History Published online 18 March 2016 Published in print April 2016 Information© Future Medicine LtdKeywordsbiofilmextracellular matrixmicroenvironmentnanomedicinenanoparticlestumorAcknowledgementsThe authors would like to thank Kenneth Sims for content feedback and artistic contribution towards Figure 1. The authors regret that several studies could only be cited indirectly from comprehensive reviews due to reference number limitations.Financial & competing interests disclosureThe authors gratefully acknowledge the NIH (K12ES019852, career development award to D Benoit; DE018023, PI: H Koo) and NSF (BMAT-DMR1206219, PI: D Benoit) for financial support. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.No writing assistance was utilized in the production of this manuscript.PDF download