胶质瘤
体内
药物输送
癌症研究
医学
U87型
药理学
全身给药
化学
生物
生物技术
有机化学
作者
Yinhsuan Michely Chen,Julien Chambon,Alexandre Moquin,Masakazu Hashimoto,Stéphanie Perrino,Matthew Leibovitch,Yasmine Benslimane,Orçun Haçarız,Qin Yang,Ichiro Nakano,Brian Meehan,Janusz Rak,Stéphane M. Gagné,Pnina Brodt
出处
期刊:Neuro-oncology
[Oxford University Press]
日期:2025-01-29
卷期号:27 (5): 1227-1240
被引量:5
标识
DOI:10.1093/neuonc/noaf011
摘要
Our results identify the IGF-Trap as a potent inhibitor of intracerebral glioma growth and show that encapsulation in nanoparticles can improve delivery of biologics such as the IGF-Trap to the brain, thereby enhancing the therapeutic response.
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