化学
芳基
废止
醋酸铵
催化作用
萘醌
有机化学
组合化学
药物化学
烷基
高效液相色谱法
作者
Ying Xie,Yulong Li,Jilan Long,Yi Liu,Huan Wang,yuxiang zhou,Hao Zhang
摘要
A novel [3 + 2] cascade reaction of aryl acetate with 1,4-dihydroxy-2-naphthoic acid ester by cooperative catalysis of isothiourea and vanadium is developed. The key step of the reaction is that the C1-ammonium enolates generated from aryl acetate will cycloadduct to 1,4-naphthoquinone intermediates. 3-Aryl-3H-benzofuranone derivatives can be prepared in medium to good yields under mild conditions.
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