黄芩苷
医学
黄芩
中医药
氧化应激
炎症
药理学
传统医学
心力衰竭
心肌梗塞
重症监护医学
生物信息学
替代医学
内科学
病理
生物
化学
高效液相色谱法
色谱法
作者
Laiyun Xin,Jialiang Gao,Hongchen Lin,Yi Qu,Chang Shang,Yuling Wang,Yingdong Lu,Xiangning Cui
标识
DOI:10.3389/fphar.2020.583200
摘要
Cardiovascular diseases (CVDs) is the leading cause of high morbidity and mortality worldwide, which emphasizes the urgent necessity to develop new pharmacotherapies. In eastern countries, traditional Chinese medicine Scutellaria baicalensisGeorgi has been used clinically for thousands of years. Baicalin is one of the main active ingredients extracted from Chinese herbal medicine S. baicalensis. Emerging evidence has established that baicalin improves chronic inflammation, immune imbalance, disturbances in lipid metabolism, apoptosis and oxidative stress. Thereby it offers beneficial roles against the initiation and progression of CVDs such as atherosclerosis, hypertension, myocardial infarction and reperfusion, and heart failure. In this review, we summarize the pharmacological features and relevant mechanisms by which baicalin regulates CVDs in the hope to reveal its application for CVDs prevention and/or therapy.
科研通智能强力驱动
Strongly Powered by AbleSci AI