Research progress on the diagnosis and treatment of low-grade appendiceal mucinous neoplasm

Objective To investigate the research progress on the diagnosis and treatment of mucinous neoplasm. Methods The keywords of low-grade mucinous , appendiceal mucinous and pseudomyxoma were used to search the related literatures in PubMed, Web of Science, CNKI, and Wanfang Date before August 2018 and to summarize the clinical diagnosis, treatment, and research of mucinous neoplasm. Results Low-grade mucinous neoplasm was one of the main pathological types of epithelial tumor, which was characterized by the stenosis of the lumen caused by chronic inflammation of the lumen caused by different reasons. Mucinous substances were constantly accumulating, and on the basis of the increasing pressure in the lumen, the mucus invaded the appendix wall or broke through the wall. The pathological diagnostic criteria of a mucinous neoplasm are more specific and helpful for diagnosis, pathological stage, and prognosis evaluation. The clinical manifestations, signs, and imaging of the tumor are better understood, which is conducive to the early detection and differential diagnosis of the disease; Its treatment method has the basic unified treatment plan in the excision scope and the mucus removal degree. Conclusions The non-specificity of clinical manifestations, the diagnostic rate of CT and ultrasound for mucinous neoplasm is gradually increasing. This tumor has a low degree of malignancy. To complete the resection of the tumor, the risk of tumor rupture should be avoided even if the resection scope is expanded. Key words: Appendiceal neoplasms; Appendiceal mucinous neoplasm; Pseudomyxoma peritonei