医学
串扰
病态的
肿瘤微环境
前列腺
旁侵犯
胰腺癌
病理
神经系统
前列腺癌
癌症
内科学
精神科
光学
物理
作者
Huan Wang,Qiming Zheng,Zeyi Lu,Liya Wang,Lifeng Ding,Liqun Xia,Hao Zhang,Tong Wang,Yi-Cheng Chen,Gonghui Li
标识
DOI:10.1038/s41420-021-00450-y
摘要
Nerves are important pathological elements of the microenvironment of tumors, including those in pancreatic, colon and rectal, prostate, head and neck, and breast cancers. Recent studies have associated perineural invasion with tumor progression and poor outcomes. In turn, tumors drive the reprogramming of neurons to recruit new nerve fibers. Therefore, the crosstalk between nerves and tumors is the hot topic and trend in current cancer investigations. Herein, we reviewed recent studies presenting direct supporting evidences for a better understanding of nerve-tumor interactions.
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