Cortico-subcortical findings in idiopathic REM sleep behavior disorder (IRBD) and Parkinson's disease: A VBM study

Idiopathic rapid eye movement sleep behavior disorder (iRBD) is a parasomnia characterized by the loss of physiological atonia with abnormal behavior during REM sleep. RBD could be the prodromal manifestation of neurodegenerative diseases, such as Parkinson's disease (PD). Neuroimaging studies showed the presence of structural and functional abnormalities involving cortical and subcortical regions in RBD.