内大麻素系统
大麻素受体
神经科学
大麻素
认知
机制(生物学)
去极化抑制抑制
心理学
受体
医学
敌手
内科学
认识论
哲学
作者
Marta Kruk-Słomka,Agnieszka Dzik,Barbara Budzyńska,Grażyna Biała
标识
DOI:10.1007/s12035-016-0313-5
摘要
The endocannabinoid system via cannabinoid (CB: CB1 and CB2) receptors and their endogenous ligands is directly and indirectly involved in many physiological functions, especially in memory and learning processes. Extensive studies reported that this system strictly modulates cognition-related processes evaluated in various animal models. However, the effects of cannabinoids on the cognition have been contradictory. The cannabinoid compounds were able to both impair or improve different phases of memory processes through direct (receptor related) or indirect (non-receptor related) mechanism. The memory-related effects induced by the cannabinoids can be depended on the kind of cannabinoid compound used, dosage, and route of administration as well as on the memory task chosen. Therefore, the objectives of this paper are to review and summarize the results describing the role of endocannabinoid system in cognition, including various stages of memory.
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