内科学
胃肠病学
炎症性肠病
C反应蛋白
克罗恩病
中性粒细胞与淋巴细胞比率
粪钙保护素
作者
Pelin Oktayoglu,Nuriye Mete,Mehmet Caglayan,Mehtap Bozkurt,Turgut Bozan,Serda Em,Kemal Nas
标识
DOI:10.3109/00365513.2014.984319
摘要
AbstractBackground. Behcet's disease (BD) is an inflammatory disease with multisystem chronic vasculitis. The disease is characterized by attacks of oral and genital ulcerations, skin lesions, arthritis, uveitis and deep vein thrombosis. The main histopathological feature is known to be vascular inflammatory change. Calprotectin (MRP8/MRP14) has been identified as an important alarmin that is expressed by activated phagocytes, granulocytes, monocytes and vascular endothelial cells, recognized by toll-like receptors, and induces a thrombogenic and inflammatory response in human microvascular endothelial cells. Aim. We aimed to investigate the serum levels of calprotectin in patients with BD and its association with disease activity and quality of life. Materials and methods. Forty-eight patients (25 males and 23 females) and 47 healthy controls (29 males and 18 females) were included to study. BD Current Activity Form (BDCAF) was used to assess the disease activity of patients with BD. Quality of life was ...
科研通智能强力驱动
Strongly Powered by AbleSci AI