Inadequate sleep and sleep deprivation can cause numerous neurobehavioral and physiological changes.A number of recent studies have reported associations between disrupted sleep or sleep deprivation and inflammatory responses, although the physiological mechanisms underlying these relationships remains unclear.Alterations in sleep due to lifestyle factors, the aging process, and disease states are all associated with increases in a range of inflammatory markers.Several of these inflammatory processes have been associated with reduced health status.Thus, maintaining adequate sleep duration and quality through good sleep habits and treatment of sleep disorders may reduce inflammatory processes associated with aging and increase the wellness phenotype.