A General Strategy toward S‐Linked Glycopeptides

Angewandte Chemie International EditionVolume 44, Issue 29 p. 4596-4599 Communication A General Strategy toward S-Linked Glycopeptides† Desiree A. Thayer, Desiree A. Thayer Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-2409 Contributed equally to this work.Search for more papers by this authorHenry N. Yu Dr., Henry N. Yu Dr. Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-2409 Contributed equally to this work.Search for more papers by this authorM. Carmen Galan Dr., M. Carmen Galan Dr. Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-2409Search for more papers by this authorChi-Huey Wong Prof., Chi-Huey Wong Prof. wong@scripps.edu Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-2409Search for more papers by this author Desiree A. Thayer, Desiree A. Thayer Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-2409 Contributed equally to this work.Search for more papers by this authorHenry N. Yu Dr., Henry N. Yu Dr. Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-2409 Contributed equally to this work.Search for more papers by this authorM. Carmen Galan Dr., M. Carmen Galan Dr. Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-2409Search for more papers by this authorChi-Huey Wong Prof., Chi-Huey Wong Prof. wong@scripps.edu Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-2409Search for more papers by this author First published: 08 July 2005 https://doi.org/10.1002/anie.200500090Citations: 59 † This work was supported by the National Institutes of Health (C.-H.W.) and National Science Foundation Predoctoral and Norton B. Gilula Graduate Student fellowships (D.A.T.). Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract A high-yield one-pot synthesis of S-linked glycosyl amino acids 1 has been developed (see scheme; DMF=dimethyl formamide) and used in the solid-phase synthesis of S-linked glycopeptides. This approach has been shown to be efficient for the synthesis of various S-linked glycosyl amino acid building blocks. Citing Literature Supporting Information Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2005/z500090_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume44, Issue29July 18, 2005Pages 4596-4599 RelatedInformation