Preparation and topographical studies of various biological specimens using alternate method to critical point drying: Scanning electron microscopy

Chemical critical drying was found to be an economic and yet effective method with less apparent deterioration of the surface features. The advantages of using a chemical dehydrant like Hexamethyldisilazane (HMDS) include ease of use, relative quickness, and less expense than a CPD. Same technique can be applied for different specimens with same results.