Novel Cyclopropene Probes as Chemical Reporters for Bioorthogonal Metabolic Labeling of Benzoylated Post-Translational Modification

. Furthermore, by using a SIRT2 inhibitor, it was confirmed that this metabolic labeling can be applied to dynamically detect changes in lysine benzoylation levels in cells. These findings provide a solid foundation for the development of novel metabolic labeling strategies for dynamically tracking post-translational modifications, particularly in live cells.